Unbreakable Bone Mutation #UnbreakableGene#BoneDensity#GeneticSuperheroes#LRP5#ScienceFacts | Prof-Hussein MA
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NOTICE IMPORTANTE : Certaines mutations du gène LRP5 (Low-Density Lipoprotein Receptor-Related Protein 5) peuvent entraîner un phénotype appelé High Bone Mass Syndrome, caractérisé par une densité osseuse anormalement élevée et une résistance accrue aux fractures. Le gène LRP5 code pour un corécepteur impliqué dans la voie de signalisation Wnt/β-caténine, un mécanisme moléculaire essentiel dans la régulation de la formation osseuse. Cette voie contrôle l’activité des ostéoblastes, cellules respo
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