Background Systemic sclerosis (SSc) is a heterogeneous disease with frequently associated interstitial lung disease (SSc-ILD). We aimed to determine the prognostic potential of phenotyping patients ...

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Background The aetiology of lung cancer among individuals who never smoked remains elusive, despite 15% of lung cancer cases in men and 53% in women worldwide being unrelated to smoking. Epigenetic ...

Correspondence to Professor Wim Janssens, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven 3000, Belgium; wim.janssens{at}uzleuven.be Rationale Estimating the ...

Background Oscillatory positive expiratory pressure (OPEP) devices are intended to facilitate sputum clearance and reduce cough, but there is limited evidence for their effectiveness in COPD, or to ...

Background Social media may influence children and young people’s health behaviour, including cigarette and e-cigarette use. Methods We analysed data from participants aged 10–25 years in the UK ...

The National Aspergillosis Centre, University Hospital of South Manchester, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK Correspondence to Dr Chris Kosmidis, ...

3 National Heart and Lung Institute, Imperial College London and Royal Brompton Hospital, London, UK Correspondence to Professor Jennifer K Quint, National Heart and Lung Institute, Imperial College ...

Dynamic lung volumes (forced vital capacity, forced expiratory volume in 0·5 second and in 1·0 second), static lung volumes (total lung capacity, functional residual capacity, residual volume), and ...

Background Tobacco smoking is a leading behavioural risk factor for death in the UK, contributing to deaths from cardiovascular disease, chronic respiratory diseases and common infectious diseases. 1 ...

Background Exacerbations of respiratory conditions including asthma are amongst the most common causes of emergency hospital attendances, but numerous pulmonary and extra-pulmonary comorbidities can ...

2 Research and Early Development, Respiratory and Immunology, BioPharmaceuticals RandD, AstraZeneca, Cambridge, UK 3 Respiratory and Immunology, Biometrics and Statistical Innovation, Late Respiratory ...