Lipid-binding sites and properties were compared in the hetero-oligomeric cytochrome (cyt) b₆f and the yeast bc₁ complexes that function, respectively, in photosynthetic and respiratory electron ...

Lipid kinases are among the promising targets of new classes of drugs, due mainly to class I PI3Kα, which plays a crucial role in carcinogenesis and metastasis. This enzyme is hyperactive in 30-40% of ...

To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction, which the ...

This project explores how a specific group of lipids, key membrane components and dynamic signaling molecules, shape cellular fate by regulating both senescence and cell death. Project is Not ...

Scientists who work with lipid nanoparticles (LNPs) say they have developed a new type of material capable of reaching the lungs and the eyes. They call their study “Thiophene-based lipids for mRNA ...

Lipid nanoparticles (LNPs) are one of the most exciting technologies in drug delivery. LNPs protect and deliver genetic material into cells, allowing a large spectrum of RNA therapeutics, including ...

This study mapped how EPA and DHA are distributed across lipid classes in microalgae, fish, krill, and commercial omega-3 ...