An international team of researchers co-led by Job Dekker, PhD, at UMass Chan Medical School, have identified rules that tell cells how to fold DNA into the tightly packed, iconic X-shaped chromosomes ...

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...

Scientists at Fred Hutchinson Cancer Research Center have worked out the molecular underpinnings of how chromosomes make the right number of crossovers — important links that make it possible for ...

For the first time, scientists have directly observed events that lead to the formation of a chromosome abnormality that is often found in cancer cells. The abnormality, called a translocation, occurs ...

Kansas City, MO—September 24, 2025—Open a high school biology textbook, and you’ll see human chromosomes lined up two by two, like socks in a drawer. But in about one out of every 800 people, two ...

Researchers have unveiled the evolutionary origin of the different chromosomal architectures found in three species of Agrobacterium. A comprehensive comparison of the Agrobacterium sequence ...

Upon entry into mitosis, loosely packed chromatin undergoes extensive compaction to form condensed chromosomes, which is essential for accurate segregation of genetic material and normal cell division ...

A hallmark of cancerous cells is an abnormal number of chromosomes or chromosome arms, known as aneuploidy. While aneuploidy ...

Robertsonian chromosomes are associated with infertility and Down syndrome, now cutting-edge DNA sequencing technology has unveiled the first comprehensive picture of their genetic rearrangements.