This is what's happening on Wednesday, as quantum computing investors cheer some kind words from Microsoft's strategic missions and technologies chief, Mitra Azizirad, who last night urged quantum investors to get ready, because "we are right on the cusp of seeing quantum computers solve meaningful problems and capture new business value."

Rigetti (RGTI) is dropping 23%, while IonQ (IONQ) is giving back 10% and D-Wave Quantum (QBTS), which disclosed today that it may sell more shares of its stock, is plunging nearly 30%. The sector is dropping sharply again after Meta (META) CEO Mark Zuckerberg suggested that quantum computing would not be “practical” for a long time.

As quantum computing matures, IonQ and D-Wave Quantum are set to play key roles in shaping the industry, providing investors with an opportunity to capitalize on one of the hottest investment themes of the decade.