Protein accidentally lassos itself, helping explain unusual refolding behavior
A new study has described a potential mechanism that could help explain why some proteins refold in a different pattern than ...
Medscape3mon
Elevated C-Reactive Protein Levels in the Development of Type 1 Diabetes
Elevated C-reactive protein ... diabetes and gestational diabetes. We hypothesized that inflammation, as reflected by elevated CRP levels, can help predict development of islet autoimmunity or ...
Medscape11d
Double Diabetes: The Silent Threat Hiding in Type 1 Patients
Insulin resistance in T1D is more common than you think, and without early intervention, these patients face increased risks ...
Nature5y
Protein Misfolding and Degenerative Diseases
As discussed already, misfolded proteins result when a protein follows the wrong folding pathway or energy-minimizing funnel, and misfolding ... diseases include type 2 diabetes, inherited ...
pharmaphorum4y
Protein Misfolding Drug Discovery Summit
join the 1 st Protein Misfolding Drug Discovery Summit – the only industry and translational focused conference, dedicated to discover and translate disruptive disease-modifying therapeutics ...
Nature4y
G-Protein-Coupled Receptors, Pancreatic Islets, and Diabetes
G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...
Business Wire19d
Paradox Immunotherapeutics Secures $10 Million Investment from SymBiosis to Advance Therapies for Protein Misfolding Diseases
TORONTO--(BUSINESS WIRE)--Paradox Immunotherapeutics (“Paradox”), a pharmaceutical company focused on the development of innovative antibody therapies that treat protein misfolding diseases ...