The spleen is a secondary lymphoid organ that is essential in the immune response against blood-borne antigens. Hematopoiesis in the spleen is mainly restricted to the production of erythrocytes, ...
The study of intraclonal diversification (ID) in immunoglobulin (IG) genes offers valuable insight into the role of ongoing interactions with antigen in lymphomagenesis. We recently showed that ID in ...
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