A computational benchmarking study found that SubPoE delivered the strongest average spatial-domain clustering results across eight paired spatial multi-omics datasets while reducing graph-processing ...

Researchers developed a new computational method to analyze complex tissue data that could transform our current understanding of diseases and how we treat them. Researchers at the University of ...

Spatial transcriptomics can reveal where thousands of genes are active across a tissue, creating molecular maps at single-cell resolution. But comparing two such maps is difficult: thin slices of ...

Spatial proteomics is a spatial biology method that helps study the spatial distribution of the proteins within cells and tissues. The subcellular localization of proteins is intrinsic to cellular ...

A new analytical framework proposes that spatial niches — recurring local cellular and molecular neighborhoods around ...