No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2009 ASCO Annual Meeting I. This abstract does not include a full text component.
Memory T lymphocytes extravasate at sites of inflammation, but the mechanisms employed by these cells to initiate contact and tethering with endothelium are incompletely understood. An important part ...
GlycoMimetics has granted Pfizer exclusive worldwide rights to develop and commercialize GMI-1070, a rationally designed glycomimetic inhibitor of E-, L- and P-selectin, for vaso-occlusive crisis ...
Leukocytes roll on selectins at nearly constant velocities over a wide range of wall shear stresses. Ligand-coupled microspheres roll faster on selectins and detach quickly as wall shear stress is ...
Edited by: Thomas W. Durso S.D. Rosen, C.R. Bertozzi, "The selectins and their ligands," Current Opinion in Cell Biology, 6:663-73, 1994. (Cited in more than 60 publications through April 1996) ...
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