Robertsonian chromosomes (ROB) are a type of structurally variant chromosome that is created when two chromosomes fuse together to form an unusual bond. Found commonly in nature, these chromosomes are ...

Repetitive elements make up over 50% of the human genome. Recent advances in long-read sequencing experimental approaches and data analysis algorithms have made it possible to characterize these ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation. Retrotransposons ...

Small plastic or metal bits at the end of shoelaces, known as aglets, prevent laces from unraveling and protect them from wear and tear. Similarly, chromosomes are capped by telomeres—specialized ...

An international team of scientists has decoded some of the most stubborn, overlooked regions of the human genome using complete sequences from 65 individuals across diverse ancestries. This milestone ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...