Major depressive disorder (MDD) is a leading cause of disability worldwide, yet many patients have inadequate responses to current treatments. Dimethyltryptamine (DMT), a serotonergic psychedelic with ...

In the 1940s, medical researchers began using randomized controlled trials to assess the efficacy of health interventions. In RCTs, researchers create randomly assigned treatment and control groups, ...

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...