Timing of troughs Troughs should be obtained at steady state: approximately prior to the fifth dose IIB Optimal trough concentrations Should be >10 mg/l at a minimum to avoid development of ...
Jennifer Le, PharmD Pediatric patients who attain higher trough levels of the drug may be at higher risk of kidney damage. SAN FRANCISCO—Nephrotoxicity from vancomycin therapy develops more quickly in ...
Expert Rev Anti Infect Ther. 2011;9(6):657-667. The impact of combination therapy upon the need for aggressive vancomycin dosing was not discussed in the guidelines but a recent review failed to find ...
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