A widely used treatment for rheumatoid arthritis may offer an unexpected cardiovascular benefit. Methotrexate has been a staple treatment for rheumatoid arthritis for decades, valued for its ability ...

Ducharme is a contributor to TIME. Ducharme is a contributor to TIME. Soon after she started taking the drug methotrexate in February, Jennifer Crow noticed a significant improvement in her ...

The RFC1 G80A polymorphism is closely associated with higher rates of methotrexate-induced toxicity in pediatric acute lymphoblastic leukemia (ALL), according to a study published in the World Journal ...

NEW YORK CITY -- Postoperative intravitreal methotrexate for retinal detachment led to a significant reduction in reoperation and improved visual acuity, a retrospective chart review showed. The ...

When news breaks, you need to understand what actually matters — and what to do about it. At Vox, our mission to help you make sense of the world has never been more vital. But we can’t do it on our ...

Methotrexate is a strong medicine. The FDA approved it to treat adults with severe, disabling psoriasis that cannot be controlled with medicine applied to the skin or light treatments. Methotrexate ...

Patients who take methotrexate for a variety of immune-mediated inflammatory diseases and pause taking the drug following receipt of a COVID-19 vaccine dose did not have a higher risk of disease flare ...

Please provide your email address to receive an email when new articles are posted on . SAN DIEGO — Split-dose methotrexate had greater efficacy and reduced the need for additional disease-modifying ...

Medically reviewed by Scott Zashin, MD Key Takeaways People taking methotrexate should avoid alcohol because it can increase the risk of liver damage.Some NSAIDs like aspirin should not be taken with ...

In July 2022, the US Food and Drug Administration (FDA) expanded the labeling of Krystexxa (pegloticase; Horizon Therapeutics), a PEGylated uric acid-specific enzyme, to include coadministration with ...

Patients with Wegener's granulomatosis often undergo treatment with cyclophosphamide in order to induce disease remission. Methotrexate and leflunomide have been proposed for maintaining remission ...

Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects. Now new research published at the ATS 2025 International ...