Researchers developed a humanized mouse model that better predicts how antibody drugs interact with the immune system. The ...

Mice with human immune cells are a new way of testing anti-cancer drugs targeting the immune system in pre-clinical studies. Using their new model, a Kobe University research team successfully tested ...

The candidate gene FKBP5 is involved in the development of stress-related psychiatric disorders. A few years ago, researchers at the MPI discovered that it is increasingly activated in the brains of ...

Please provide your email address to receive an email when new articles are posted on . The FDA approved the first chimeric antigen receptor therapy in 2017, authorizing tisagenlecleucel for treatment ...

In vivo models of human immunity in human tumor-bearing mice are frequently used to study mechanisms of targeted immunotherapies, safety, and efficacy. In a recent webinar Jenny Rowe, PhD, Scientist ...

Immunotherapy harnesses a patient’s own immune system to combat cancer, with numerous benefits compared to conventional treatments such as chemotherapy and surgical removal. 1 Among different ...

Mice are commonly used as models of human disease, helping scientists to understand the workings of complex pathologies and develop safe and efficacious drugs. It is now possible to create a range of ...

Figure 1: VIP protects against CD4 + T cell depletion in humanized mice resulting from challenge with CCR5-tropic or transmitted founder HIV strains. Figure 2: VIP prevents mucosal transmission of ...

In a bid to improve organ transplant options in the future, a team led by researchers at the Chinese Academy of Sciences has shown that it's possible to produce pig embryos containing "humanized" ...