Replication of the genome during the S phase of the cell cycle increases the DNA dose of newly replicated genes, but in eukaryotic cells, the mRNA expression levels of these genes do not increase ...
Sometimes a replicating cell must choose the lesser of two evils. For example, when a replicating cell is stressed, it may struggle to pair bases against its single-stranded DNA (ssDNA) template, even ...
Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently ...
Failures in DNA replication can lead to cancer, birth defects or other harm Video shows single pieces of double-helix DNA being copied Single-molecule view gives new insights into this process ...
In a study that appears in the journal Cell, scientists from San Francisco-based Gladstone Institutes—including co-first author Megan Ostrowski (left) and senior author Vijay Ramani, PhD ...
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DNA from the mother and father are handled differently in the newly formed embryo, researchers discover
Researchers at the Center for Embryology and Healthy Development (CRESCO) aim to find out why so many early embryos fail in their development. New insights into how maternal and paternal DNA is ...
Researchers have discovered how a key function of the AND-1 protein helps protect nascent DNA strands from degradation. Researchers from Tokyo Metropolitan University and the FIRC Institute of ...
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