To understand the pharmacology and mechanism of action of ximelagatran, a review of the formation and function of thrombin is warranted. [10] The generation of thrombin is limited under normal ...
Middle East respiratory syndrome (MERS) is associated with a mortality rate of >35%. We previously showed that MERS coronavirus (MERS-CoV) could infect human macrophages and dendritic cells and induce ...
When injured, endothelial cells permit granulocytes and plasma constituents to enter inflamed tissue, which may lead to organ damage. Endothelial cell inflammation causes vasodilation through the ...
In the general biochemistry course I teach at Oregon State University, one of the topics students find both fascinating and complex is that of blood coagulation. It’s not without good reason, in my ...