Researchers at Umeå University have conducted a unique three-dimensional mapping of an entire human pancreas. The study shows that insulin-producing cells can remain long after the onset of type 1 ...
Hormone systems, which control diverse physiological functions, have been extensively studied, yet consistent rules underlying these systems remain elusive. Here we identify unifying design principles ...
Remarkable advances in protocol development have been achieved to manufacture insulin-secreting islets from human pluripotent stem cells (hPSCs). Distinct from current approaches, we devised a tunable ...
When these hormones become imbalanced, it can lead to the development of an endocrine disorder. “An endocrine disorder occurs when your body produces either too much or too little of a particular ...
Immunofluorescence image of the pancreatic islets of a 50-year-old-female without diabetes. This individual had 54% beta cells (GREEN), 9% delta cells (WHITE) and 37% alpha cells (RED). Diabetes is ...
(A) Representative H&E staining image of a mouse pancreas. The black arrow denotes the acinar cells and the white arrow denotes the islet. (B) Representative image of electron microscopy analysis of ...