DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a number of ...

Researchers at the Weill Institute for Cell and Molecular Biology have uncovered new evidence that two major types of gene-controlling DNA sequences, promoters and enhancers, operate with a shared ...

A team led by Professor Inkyung Jung from the Department of Biological Sciences at KAIST, working with Professor Yarui Diao’s ...

Acetylation of histone H3 at the nucleosome surface is associated with destabilised nucleosomes and is a useful new functional genomics mark for identifying regulatory regions of the mammalian genome.

SynGenSys, a biotechnology company designing synthetic gene promoter systems to address critical bottlenecks in biopharma manufacturing and enhance cell and gene therapy development, today announced ...

Cardiovascular disease remains the leading cause of mortality worldwide, necessitating deeper insights into its molecular underpinnings beyond genetic predisposition. Epigenetic modifications, ...

Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily.

Flowering time determines reproductive success in perennial trees, yet the epigenetic mechanisms underlying sexual asynchrony remain poorly understood.