Nature

An integrated model for detecting significant chromatin interactions from high-resolution Hi-C data

Here we present HiC-DC, a principled method to estimate the statistical significance (P values) of chromatin interactions from Hi-C experiments. HiC-DC uses hurdle negative binomial regression account ...
The New England Journal of Medicine

Four-Year Efficacy of RTS,S/AS01E and Its Interaction with Malaria Exposure

The candidate malaria vaccine RTS,S/AS01E has entered phase 3 trials, but data on long-term outcomes are limited. Over a period of 4 years, 118 of 223 children who received the RTS,S/AS01E vaccine and ...
JSTOR Daily

OPTIMAL DESIGN FOR MULTIPLE REGRESSION WITH INFORMATION DRIVEN BY THE LINEAR PREDICTOR

In this paper we consider nonlinear models with an arbitrary number of covariates for which the information additionally depends on the value of the linear predictor. We establish the general result ...
ascopubs.org

Race and Insurance Differences in the Receipt of Adjuvant Chemotherapy Among Patients With Stage III Colon Cancer

Final Results of a Prospective Evaluation of the Predictive Value of Interim Positron Emission Tomography in Patients With Diffuse Large B-Cell Lymphoma Treated With R-CHOP-14 (SAKK 38/07) Patients ...
ascopubs.org

Prostate specific antigen testing as disease surveillance and monitoring five years after definitive therapy for localized prostate cancer.

Tumor response to a mastermind inhibitor protein. Multivariate log-binomial regression model for patients not receiving at least one PSA surveillance test over the first 5 Years post-definitive ...