America should have more aggressively intervened almost a year ago.

A variant of the virus caused disease in people in 1997, when there was a small but deadly outbreak in Hong Kong. Eighteen people had confirmed diagnoses, and six of them died. Since then, there have been sporadic cases around the world—but no large outbreaks.

The first human death from bird flu in the United States has intensified calls for the government to ramp up efforts to stave off the threat of another pandemic -- particularly ahead of Donald Trump's return to the White House.

A Louisiana patient is the first person in the United States to die as a result of H5N1 infection. One expert likens what happens next to Russian roulette.

The patient, who was older than 65 and had underlying medical conditions, was hospitalized weeks ago in critical condition with severe respiratory illness.

How deadly is the bird flu? The US has reported its first death from avian influenza, H5N1. Here's what to know about bird flu mortality rate and who is at risk.

The death in Louisiana — involving a person with underlying health conditions — is the first human case in the United States linked to exposure to backyard birds, according to the federal Centers for Disease Control and Prevention.

Any time a person catches H5N1, or bird flu, their infection is a chance for the virus to mutate in the wrong direction. When someone dies from the bird flu—as an elderly Louisiana man did on Jan. 6,

The bird flu virus circulating among cows, poultry and wild birds isn't yet a threat to the general public, but experts say if and when that will change is impossible to predict — and that if things do get bad,

Read more Bird flu has been spreading into Texas, and Texas Parks and Wildlife Division (TPWD) said it recently found cases in Travis, Wharton, Galveston, El Paso, Potter and Harris counties.